Towards analytically useful two-dimensional Fourier transform ion cyclotron resonance mass spectrometry
نویسندگان
چکیده
منابع مشابه
Towards analytically useful two-dimensional Fourier transform ion cyclotron resonance mass spectrometry.
Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometry (MS) achieves high resolution and mass accuracy, allowing the identification of the raw chemical formulae of ions in complex samples. Using ion isolation and fragmentation (MS/MS), we can obtain more structural information, but MS/MS is time- and sample-consuming because each ion must be isolated before fragmentation. In 1987,...
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This review offers an introduction to the principles and generic applications of FT-ICR mass spectrometry, directed to readers with no prior experience with the technique. We are able to explain the fundamental FT-ICR phenomena from a simplified theoretical treatment of ion behavior in idealized magnetic and electric fields. The effects of trapping voltage, trap size and shape, and other nonide...
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The kinetic energy-dependent Ar(+)+ N2 ion-molecule reaction has been used as a chemical "thermometer" to determine the kinetic energy of ions produced by electron ionization and trapped by using a Fourier transform ion cyclotron resonance (FTICR) mass spectrometer. The rate constant for this reaction obtained on the FTICR mass spectrometer was compared to previous work, which allowed a kinetic...
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Mass spectrometry imaging (MSI) is a powerful tool in metabolomics and proteomics for the spatial localization and identification of pharmaceuticals, metabolites, lipids, peptides and proteins in biological tissues. However, sample preparation remains a crucial variable in obtaining the most accurate distributions. Common washing steps used to remove salts, and solvent-based matrix application,...
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ژورنال
عنوان ژورنال: Analytical and Bioanalytical Chemistry
سال: 2012
ISSN: 1618-2642,1618-2650
DOI: 10.1007/s00216-012-6422-8